Biomol/2-花生四烯醇甘油/10 mg/Cay62160-10
商品编号：
Cay62160-10
品牌：
Biomol
市场价：
¥3760.00
美元价：
1880.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Product information "2-Arachidonoyl Glycerol"
2-Arachidonoyl glycerol (2-AG) is an endogenous agonist of the cannabinoid (CB) receptors CB1 and CB2 (Kis = 25.3-472 and 145-1,400 nM, respectively). Unlike arachidonoyl ethanolamide (AEA, Cay-90050), 2-AG is present at relatively high levels in the central nervous system and is the most abundant molecular species of monoacylglycerol (MAG) found in rat brain. Formation of 2-AG is calcium-dependent and is mediated by the activities of phospholipase C (PLC) and diacylglycerol (DAG) lipase. 2-AG acts as a full agonist at the CB1 receptor. At a concentration of 0.3 nM, 2-AG induces a rapid, transient increase in intracellular free calcium in NG108-15 neuroblastoma X glioma cells through a CB1 receptor-dependent mechanism. 2-AG is metabolized in vitro by MAG lipase and fatty acid amide hydrolase (FAAH), with MAG lipase likely being the principle metabolizing enzyme in vivo.
| Keywords: | 2-AG, 5Z,8Z,11Z,14Z-eicosatetraenoic acid, 2-glyceryl ester |
| Supplier: | Cayman Chemical |
| Supplier-Nr: | 62160-1 |
Properties
| Application: | CB1 receptor agonist |
| MW: | 378.6 D |
| Formula: | C23H38O4 |
| Purity: | >95% (as a 9:1 mixture of the 2-AG and 1-AG) |
| Format: | Solution |
Database Information
| CAS : | 53847-30-6| Find alternatives |
Handling & Safety
| Storage: | -80°C |
| Shipping: | -20°C (International: -80°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |   |
| H Phrases: | H225, H302, H312, H319, H332 |
| P Phrases: | P210, P233, P240, P241, P242, P243, P261, P264, P270, P271, P280, P312, P321, P330, P301+P310, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P337+P313, P361+P364, P370+P378, P403+P235, P501 |
Caution Our products are for laboratory research use only: Not for administration to humans!
品牌介绍
抗体在Biomol，您将找到适合您的研究的正确的多克隆或单克隆抗体。选择偶联（标记）的一抗（例如，FITC和生物素）用于抗原的直接免疫检测，或一抗加上二抗用于间接抗原检测。免疫球蛋白G类（IgG）的抗体主要用于免疫学检测。它们由四个蛋白质链组成：两条分子量为25 kDa的轻链（L）和两条分子量分别为50 kDa的重链（H）。由二硫键连接的重链和轻链（H + L）一起形成了众所周知的抗体结构。对于某些实验，这些免疫球蛋白的酶消化产生具有优势性质的抗体片段。
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