表达Biomol/Cas9的Raji细胞池/2 MCells/BPS-78071
市场价:
¥19960.00
美元价:
9980.00
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Product information "Cas9 Expressing Raji cell pool"
Cas9 (Streptococcus pyogenes CRISPR associated protein 9) is an endonuclease enzyme that, when recruited to a specific DNA sequence by the sgRNA (single guide RNA), introduces a double stranded break into the DNA. This double stranded break is repaired in mammalian cells either through Non-Homologous End Joining or Homologous Recombination. Non-Homologous End Joining often results in the deletion or insertion of several base pairs at the cut site, which, when resulting in a frameshift, causes the functional inactivation of the targeted gene. Cas9 expressing Raji cells can be transduced or electroporated with sgRNA targeting a gene of interest to quickly generate knock-out cell pools or cell lines.
Keywords: | SpCas9, SpyCas9, SPy_1046, CRISPR-associated endonuclease Cas9/Csn1 |
Supplier: | BPS Bioscience |
Supplier-Nr: | 78071 |
Properties
Application: | Quick knock-out cell pool / cell line generation, SgRNA screening |
Reactivity: | Human |
Database Information
KEGG ID : | K09952 | Find alternatives |
UniProt ID : | Q99ZW2 | Find alternatives |
Handling & Safety
Storage: | Liquid nitrogen (store in liquid nitrogen) |
Shipping: | -80°C (International: °C) |
Caution Our products are for laboratory research use only: Not for administration to humans!
品牌介绍
抗体在Biomol,您将找到适合您的研究的正确的多克隆或单克隆抗体。选择偶联(标记)的一抗(例如,FITC和生物素)用于抗原的直接免疫检测,或一抗加上二抗用于间接抗原检测。免疫球蛋白G类(IgG)的抗体主要用于免疫学检测。它们由四个蛋白质链组成:两条分子量为25 kDa的轻链(L)和两条分子量分别为50 kDa的重链(H)。由二硫键连接的重链和轻链(H + L)一起形成了众所周知的抗体结构。对于某些实验,这些免疫球蛋白的酶消化产生具有优势性质的抗体片段。
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