Biomol/AMPK-ACC pathway Antibody Panel/1 kit (1 kit)/ARG30182.1
商品编号：
ARG30182.1
品牌：
Biomol
市场价：
¥15520.00
美元价：
7760.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Product information "AMPK-ACC pathway Antibody Panel"
AMP-activated protein kinase (AMPK) responds to hormonal and nutrient signals in the central nervous system and peripheral tissues, modulating food intake and whole-body energy homeostasis. The kinase is activated by an elevated AMP/ATP ratio due to cellular and environmental stress, such as heat shock, hypoxia and ischemia. Phosphorylates AMPKalpha1/2 at Thr172/Thr174 in the activation loop and this phosphorylation is required for AMPK activation. . In its activated state, AMPK phosphorylates serine residues 79, 1,200, and 1,215 of acetyl-coenzyme A carboxylase (ACC) which is reducing the activity of ACC. ACC is a potential target of anti-obesity drugs.
| Keywords: | Anti-AMPK, Anti-PRKAA2, EC=2.7.11.1, Anti-HMGCR kinase, EC=2.7.11.27, EC=2.7.11.31, Anti-ACACA kinase, Anti-AMPK subunit alpha-2, Anti-Acetyl-CoA carboxylase kinase, Anti-Hydroxymethylglutaryl-CoA reductase kinase |
| Supplier: | Arigo Biolaboratories |
| Supplier-Nr: | ARG30182001 |
Properties
| Application: | WB |
| Antibody Type: | Mixed |
| Conjugate: | No |
| Reactivity: | Human |
Database Information
| KEGG ID : | K07198 | Find alternatives |
| UniProt ID : | P54646 | Find alternatives |
| Gene ID | GeneID 5563 | Find alternatives |
Handling & Safety
| Storage: | vT |
| Shipping: | +4°C (International: +4°C) |
Caution Our products are for laboratory research use only: Not for administration to humans!
品牌介绍
抗体在Biomol，您将找到适合您的研究的正确的多克隆或单克隆抗体。选择偶联（标记）的一抗（例如，FITC和生物素）用于抗原的直接免疫检测，或一抗加上二抗用于间接抗原检测。免疫球蛋白G类（IgG）的抗体主要用于免疫学检测。它们由四个蛋白质链组成：两条分子量为25 kDa的轻链（L）和两条分子量分别为50 kDa的重链（H）。由二硫键连接的重链和轻链（H + L）一起形成了众所周知的抗体结构。对于某些实验，这些免疫球蛋白的酶消化产生具有优势性质的抗体片段。
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