用于激活/抑制位点抗体面板的Biomol/Phospho-Smad1/1试剂盒(1试剂盒)/ARG30155.1
商品编号:
ARG30155.1
品牌:
Biomol
市场价:
¥15520.00
美元价:
7760.00
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Product information "Phospho-Smad1 for Activation/Inhibition site Antibody Panel"
Smad transcription factors convey downstream messages from the most versatile cytokine signaling pathways in the multicellular life forms, the transforming growth factor-beta (TGFbeta) pathway. Recent works has shed light into the processes and functions of SMAD activation and deactivation, nucleocytoplasmic dynamics, and assembly of transcriptional complexes. Smad proteins consist of two globular domains coupled by a linker region. Smad1 can be phosphorylated at the linker region (pSer206) where recruitment of Smurf takes place and results in the degradation of Smad1. On the other hands, phosphorylation of Smad1 at pSer465 translocate Smad1/Smad4 complex to nucleus and transcriptionally activate target genes.
Keywords: | Anti-phospho-BSP1, Anti-phospho-Smad1, Anti-phospho-JV4-1, Anti-phospho-SMAD1, Anti-phospho-BSP-1, Anti-phospho-hSMAD1, Anti-phospho-SMAD 1, Anti-phospho-MAD homolog 1, Anti-phospho-SMAD family member 1, Anti-phospho-Mad-related protein 1 |
Supplier: | Arigo Biolaboratories |
Supplier-Nr: | ARG30155001 |
Properties
Application: | WB |
Antibody Type: | Mixed |
Conjugate: | No |
Reactivity: | Human, Mouse, Rat |
Database Information
KEGG ID : | K04676 | Find alternatives |
UniProt ID : | Q15797 | Find alternatives |
Gene ID | GeneID 4086 | Find alternatives |
Handling & Safety
Storage: | vT |
Shipping: | +4°C (International: +4°C) |
Caution Our products are for laboratory research use only: Not for administration to humans!
品牌介绍
抗体在Biomol,您将找到适合您的研究的正确的多克隆或单克隆抗体。选择偶联(标记)的一抗(例如,FITC和生物素)用于抗原的直接免疫检测,或一抗加上二抗用于间接抗原检测。免疫球蛋白G类(IgG)的抗体主要用于免疫学检测。它们由四个蛋白质链组成:两条分子量为25 kDa的轻链(L)和两条分子量分别为50 kDa的重链(H)。由二硫键连接的重链和轻链(H + L)一起形成了众所周知的抗体结构。对于某些实验,这些免疫球蛋白的酶消化产生具有优势性质的抗体片段。
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