生物醇/放线菌素D/5 mg/Cay11421-5
商品编号：
Cay11421-5
品牌：
Biomol
市场价：
¥1300.00
美元价：
650.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Product information "Actinomycin D"
Actinomycin D is a cyclic polypeptide-containing antibiotic that binds to DNA and blocks transcription. It binds to pre-melted double-stranded DNA in transcription bubbles and once bound is slow to dissociate. DNA in transcriptionally hyperactive cancer cells efficiently and rapidly bind actinomycin D at low concentrations (~10 nM), which interferes with RNA synthesis and ultimately leads to cell death. Actinomycin D is widely used as an anticancer agent for treating a variety of tumors and along with its fluorescent derivative, 7-aminoactinomycin D (Cay-11397) has become a useful tool in biochemistry and molecular biology research as a marker for DNA.
| Keywords: | Cosmegen, Dactinomycin, Meractinomycin, NCI C04682, NSC 3053, Oncostatin K, 2-amino-N,N"-bis(hexadecahydro-6,13-diisopropyl-2,5,9-trimethyl-1,4,7,11,14-pentaoxo-1H-pyrrolo[2,1-i][1,4,7,10,13]oxatetraazacyclohexadecin-10-yl)-4,6-dimethyl-3-oxo-3H-phenoxazi |
| Supplier: | Cayman Chemical |
| Supplier-Nr: | 11421-5 |
Properties
| Application: | Cancer studies, Antineoplastic |
| MW: | 1255.5 D |
| Formula: | C62H86N12O16 |
| Purity: | >95% |
| Format: | Crystalline Solid |
Database Information
| CAS : | 50-76-0| Find alternatives |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: -20°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |    |
| H Phrases: | H300, H317, H334, H350, H360 |
| P Phrases: | P201, P202, P261, P264, P270, P272, P280, P284, P321, P330, P301+P310, P302+P352, P304+P341, P308+P313, P333+P313, P342+P311, P362+P364, P405, P501 |
Caution Our products are for laboratory research use only: Not for administration to humans!
品牌介绍
抗体在Biomol，您将找到适合您的研究的正确的多克隆或单克隆抗体。选择偶联（标记）的一抗（例如，FITC和生物素）用于抗原的直接免疫检测，或一抗加上二抗用于间接抗原检测。免疫球蛋白G类（IgG）的抗体主要用于免疫学检测。它们由四个蛋白质链组成：两条分子量为25 kDa的轻链（L）和两条分子量分别为50 kDa的重链（H）。由二硫键连接的重链和轻链（H + L）一起形成了众所周知的抗体结构。对于某些实验，这些免疫球蛋白的酶消化产生具有优势性质的抗体片段。
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