Biomol/Anhydrotetracycline (hydrochloride)/250 mg/Cay10009542-250
商品编号：
Cay10009542-250
品牌：
Biomol
市场价：
¥3160.00
美元价：
1580.00
产品分类：
标记试剂盒
公司分类：
Labeling_Kit
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Product information "Anhydrotetracycline (hydrochloride)"
The tetracycline repressor (TetR) is a transcriptional regulator which normally binds tightly to its palindromic tetO operator DNA, blocking gene expression. Tet causes the repressor to dissociate from the DNA, allowing transcription to occur. A novel reverse TetR (revTetR) requires tetracycline as a co-repressor to bind tetO and block transcription. Anhydrotetracycline (hydrochloride) is a powerful effector in both the tetracycline repressor (TetR) and reverse TetR (revTetR) systems, binding the Tet repressor 35-fold more strongly than Tet. Moreover, anhydrotetracycline poorly binds the 30S ribosomal subunit, compared to Tet, so it does not act as a general inhibitor of translation and is a poor antibiotic. Perhaps related to this, the concentration of anhydrotetracycline that inhibits eukaryotic cell growth is more than a 1,000-fold above the dose that alters transcription through TetR.
| Keywords: | 4-(dimethylamino)-1,4S,4aS,5,12,12aS-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-2-naphthacenecarboxamide, monohydrochloride |
| Supplier: | Cayman Chemical |
| Supplier-Nr: | 10009542-50 |
Properties
| Application: | Antibiotic |
| MW: | 462.9 D |
| Formula: | C22H22N2O7 . HCl |
| Purity: | >98% |
| Format: | Crystalline Solid |
Database Information
| CAS : | 13803-65-1| Find alternatives |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: -20°C) |
Caution Our products are for laboratory research use only: Not for administration to humans!
品牌介绍
抗体在Biomol，您将找到适合您的研究的正确的多克隆或单克隆抗体。选择偶联（标记）的一抗（例如，FITC和生物素）用于抗原的直接免疫检测，或一抗加上二抗用于间接抗原检测。免疫球蛋白G类（IgG）的抗体主要用于免疫学检测。它们由四个蛋白质链组成：两条分子量为25 kDa的轻链（L）和两条分子量分别为50 kDa的重链（H）。由二硫键连接的重链和轻链（H + L）一起形成了众所周知的抗体结构。对于某些实验，这些免疫球蛋白的酶消化产生具有优势性质的抗体片段。
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