Biomol/前列腺素D2-d4/50µg/Cay312010-50
商品编号:
Cay312010-50
品牌:
Biomol
市场价:
¥3580.00
美元价:
1790.00
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Product information "Prostaglandin D2-d4"
Prostaglandin D2-d4 (PGD2-d4) contains four deuterium atoms at the 3, 3", 4, and 4" positions. It is intended for use as an internal standard for the quantification of PGD2 by GC- or LC-mass spectrometry. PGD2 is the major eicosanoid product of mast cells and is released in large quantities during allergic and asthmatic anaphylaxis. Mastocytosis patients produce excessive amounts of PGD2, which causes vasodilation, flushing, hypotension, and syncopal episodes. PGD2 is also produced in the brain via an alternative pathway involving a soluble, secreted PGD-synthase also known as beta-trace.2,3 In the brain, PGD2 produces normal physiological sleep and lowering of body temperature. Further pharmacological actions include inhibition of platelet aggregation and relaxation of vascular smooth muscle. PGD2 inhibits human ovarian tumor cell proliferation with an IC50 of 6.8 µM.
Keywords: | PGD2-d4, 9alpha,15S-dihydroxy-11-oxo-prosta-5Z,13E-dien-1-oic-3,3,4,4-d4 acid |
Supplier: | Cayman Chemical |
Supplier-Nr: | 312010-25 |
Properties
Application: | Standard |
MW: | 356.5 D |
Formula: | C20H28D4O5 |
Purity: | >99% deuterated forms (d1-d4) |
Format: | Solution |
Database Information
CAS : | 211105-29-2| Find alternatives |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Signal Word: | Danger |
GHS Hazard Pictograms: | |
H Phrases: | H225, H319, H336, EUH066 |
P Phrases: | P210, P240, P241, P242, P243, P261, P264, P271, P280, P312, P303+P361+P353, P304+P340, P305+P351+P338, P337+P313, P370+P378, P405, P403+P233, P403+P235, P501 |
Caution Our products are for laboratory research use only: Not for administration to humans!
品牌介绍
抗体在Biomol,您将找到适合您的研究的正确的多克隆或单克隆抗体。选择偶联(标记)的一抗(例如,FITC和生物素)用于抗原的直接免疫检测,或一抗加上二抗用于间接抗原检测。免疫球蛋白G类(IgG)的抗体主要用于免疫学检测。它们由四个蛋白质链组成:两条分子量为25 kDa的轻链(L)和两条分子量分别为50 kDa的重链(H)。由二硫键连接的重链和轻链(H + L)一起形成了众所周知的抗体结构。对于某些实验,这些免疫球蛋白的酶消化产生具有优势性质的抗体片段。
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