Biomol/瓜氨酸化组蛋白H3（克隆11D3）ELISA试剂盒/96孔/Cay501620-96
商品编号：
Cay501620-96
品牌：
Biomol
市场价：
¥12380.00
美元价：
6190.00
产品分类：
反转录酶
公司分类：
Reverse_transcriptase
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Product information "Citrullinated Histone H3 (Clone 11D3) ELISA Kit"
Histone H3 is citrullinated by peptidylarginine deiminase 4 (PAD4) at residues R2, R8, and R17 during the processes of epigenetic chromatin remodeling and neutrophil extracellular trap (NET) formation. In vitro, citrullinated H3 (CitH3) is released from neutrophils that have been stimulated with calcium ionophore during the process of NETosis, and can be freed from NETs by treatment with nuclease. The measurement of CitH3, either in cell lysates or released during NETosis can be used as a functional readout of pharmacological PAD inhibition.
| Keywords: | CitH3 (Clone 11D3) EIA Kit |
| Supplier: | Cayman Chemical |
| Supplier-Nr: | 501620-96 |
Properties
| Application: | ELISA |
| Clone: | 11D3 |
| Format: | Solid Phase |
Database Information
| KEGG ID : | K11253 | Find alternatives |
| UniProt ID : | P68431 | Find alternatives |
| Gene ID | GeneID 8350 | Find alternatives |
Handling & Safety
| Storage: | -20°C |
| Shipping: | -20°C (International: -20°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |  |
| H Phrases: | H315 |
| P Phrases: | P264, P280, P321, P302+P352, P332+P313, P362+P364 |
Caution Our products are for laboratory research use only: Not for administration to humans!
品牌介绍
抗体在Biomol，您将找到适合您的研究的正确的多克隆或单克隆抗体。选择偶联（标记）的一抗（例如，FITC和生物素）用于抗原的直接免疫检测，或一抗加上二抗用于间接抗原检测。免疫球蛋白G类（IgG）的抗体主要用于免疫学检测。它们由四个蛋白质链组成：两条分子量为25 kDa的轻链（L）和两条分子量分别为50 kDa的重链（H）。由二硫键连接的重链和轻链（H + L）一起形成了众所周知的抗体结构。对于某些实验，这些免疫球蛋白的酶消化产生具有优势性质的抗体片段。
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